Relying on over 20 years of experience in the field of antibody engineering and supported in part by The National Science Foundation, GlobalBio, Inc. was founded in 2014 to develop methods to engineer better and more developable therapeutic antibodies.

Based on these methods, GlobalBio has signed and executed numerous contracts to optimize and develop antibody-based therapeutics for use in Immuno-Oncology, Oncology and Infectious Diseases.

The founder, Dr. Juan C. Almagro, is an internationally-recognized expert in the engineering and development of antibody-based therapeutics. He held positions of Senior Director at Pfizer and Research Fellow and Head of Antibody Design at Janssen Biopharmacetic (Johnson and Johnson).

RELEVANT PUBLICATIONS
INVITED REVIEWS
BOOK CHAPTERS
RELEVANT PATENTS

  • RELEVANT PUBLICATIONS

  • BOOK CHAPTERS

  • RELEVANT PATENTS

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Chen J, Fransson J, Fursov N, Hamel D, Malia T, Obmolova G, Ort T, Rycyzyn M, Scully M, Sweet R, Teplyakov A, Wheeler J, Almagro JC. Nucleic acid molecules encoding anti-CD27 antibodies JANSSEN BIOTECH, INC. US Patent: 9,683,046. Issued: 06/20/2017.

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Almagro JC, Dubell W, Fransson J, Swanson RV, Pardinas J. Human Oncostatin M antibodies and methods of use. US Patent: 9,163,083. Assignee: JANSSEN BIOTECH, INC. Issued: 10/20/2015.

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Chen J, Fransson, J, Fursov N, Hamel D, Malia T, Obmolova G, Ort T, Rycyzyn M, Scully M, Sweet R, Teplyakov A, Wheeler J, Almagro JC. Human anti-CD27 antibodies, methods and uses. US Patent: 9,102,737. Assignee: JANSSEN BIOTECH, INC. Issued: 08/11/2015.

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Tsui P, Luo J, Bernard A, Shi L, Jin Lu Wheeler J, Whitaker B, Borozdina-Birch L, Almagro JC, Tornetta M, Reddy R, Knight DM, Sweet SW, Chen Q. Generation of Human De Novo pIX Phage Display Libraries. US Patent: 9,062,305. Assignee: JANSSEN BIOTECH, INC. Issued: 06/23/2015.

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Almagro JC, Anderson GM, Chi E, Martinez C, Raghunathan G, Swanson R, Teplyakov A, Tse K-F, Wu S-J, Zhou; Hong M. Human tissue factor antibody and uses thereof. US Patent: 8,999,333 Assignee: JANSSEN BIOTECH, INC. Issued: 04/07/2015.

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Almagro JC, Branigan P, Colleen K, Strohl W, Taudte S, Torneta M, Wheelers J. Humanized IL-25 Antibodies. US Patent: 8,785,605. Assignee JANSSEN BIOTECH, INC. Issued: 07/22/2014.

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Almagro JC, Fransson J, Raghunathan R. Method of Affinity Maturing Antibodies. US Patent: 8,580,714. Assignee: JANSSEN BIOTECH, INC. Issued: 11/12/2013.

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Almagro JC, Della Ducate D, Elloso M, Luo J, Malia T, Naso M, Obmolova G, Rauchenberger R, Rutz M, Wu B, Wu SJ. IL-17A antibodies. US Patent: 8,519,107. Assignee: JANSSEN BIOTECH, INC. Issued: 8/27/2013.

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Swanson RV, Chi E, Raghunathan G, Zhao S, Fransson J, Cordier W, Almagro JC, Hyun L, Giles-Komar J, O'Neil KT, Carton JM, Zhou HM, Teplyakov AV, Feng Y. Engineered Anti-IL-13 Antibodies, Compositions, Methods and Uses. US Patent: 8,399,630. Assignee: Centocor Ortho Biotech Inc. Issued: 19/03/2013.

  • Invited Reviews